|
KMID : 0370219970410020268
|
|
Yakhak Hoeji
1997 Volume.41 No. 2 p.268 ~ p.272
|
|
|
Suppression of Immediate Hypersensitivity by Methyleugenol
|
|
김창영/Kim CY
신태용/김형민/Shin TY/Kim HM
|
|
|
Abstract
|
|
|
|
We studied the action of methyleugenol on immediate hypersensitivity. Methyleugenol completely inhibited systemic anaphylaxis induced by compound 48/80 in mice. Methyleugenol also inhibited local anaphylaxis induced by anti-dinitrophenyl (DNP) IgE. Moreover, methyleugenol dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80 or anti-DNP IgE. These results suggest that the inhibitory effect of methyleugenol on anaphylaxis induced by compound 48/80 or anti-DNP IgE is due to, in part at least, the membrane stabilization of mast cells.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|